Also at the Accra Sports Stadium on Saturday, it is a do-or-die affair as relegation-threatened Great Olympics host struggling Asante Kotoko in a game that both need the three points desperately to ease the mounting pressure.
Indeed, all the matches are tricky and it will be a real battle as clubs seek to finish the first round on a bright note.
At the El Wak Stadium on Sunday, Inter Allies will host Bolga All Stars, Medeama also hosts Elmina Sharks, while Ashgold travel to Cape Coast to face Ebusua Dwarfs.
Wa All Stars who beat Olympics 1-0 in their GPL outstanding game last weekend, host Bechem United, George Afriyie’s Liberty Professionals welcome Wilfred Kweku Osei’s Tema Youth.
Another must watch game, will be at the Nana Agyeman Park at Dormaa where Aduana Stars host regional rivals, Berekum Chelsea.